BST

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BST

(convention)
British Summer Time. The name for daylight-saving time in the UK GMT time zone.
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References in periodicals archive ?
BST-2/ tetherin: a new component of the innate immune response to enveloped viruses.
Antiviral potency and functional analysis of tetherin orthologues encoded by horse and donkey.
Bieniasz, "Vpu binds directly to tetherin and displaces it from nascent virions," PLoS Pathogens, vol.
Wilson et al., "The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin," PLoS Pathogens, vol.
Cohen's team explained how the Vpu viral protein prevents the expression of Tetherin, a host factor inhibiting HIV-1 release, on the surface of infected cells.Thus, if researchers manage to develop small molecules that prevent Vpu binding to Tetherin, this would restore one of the natural defence mechanisms that prevent the production, transmission and spread of HIV-1.The study by Dr.
The work allowed the research team to design a completely artificial protein-one that did not resemble native tetherin in its sequence at all-that could nonetheless put a similar stop to the virus.
"Tetherin is essentially a rod with anchors at either end that are critical for its function," says Paul Bieniasz of Howard Hughes Medical Institute and the Aaron Diamond AIDS Research Center at The Rockefeller University.
Evidence has also shown that some cell proteins--dubbed "tetherins"--have the ability to force new retrovirus particles to simply attach to the cell surface rather than invade it.
Cai et al., "The interferon-inducible protein tetherin inhibits hepatitis B virus virion secretion," Journal of Virology, vol.
Guo, "Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms," Journal of Virology, vol.
"Tetherin represents a new class of cellular factors that possess a very different means of inhibiting viral replication," says study author Paul Bates, PhD, Associate Professor of Microbiology at the University of Pennsylvania School of Medicine.
This set of IFN-stimulated genes (ISGs) contained several genes with previously known direct antiviral activity, such as APOL9, BST2 (Tetherin), DDX58 (RIG-1), EIF2AK2 (PKR), IFITM3, ISG15, MX2, OAS-1, PARP12, or TRIM.