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(US), anesthetic
a substance that causes anaesthesia
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a substance that acts selectively on the central nervous system and induces a state of anesthesia.

The meaning of the term “anesthetic” has changed in the course of the development of pharmacology. Anesthetics used to include nervous-system depressants and stimulants, as well as many substances that only indirectly affect the nervous system. From the beginning of anesthetic practice, stimulants, depressants, and various indirectly acting substances were the principal anesthetics. Neurotropic agents with different types of action, for example, analgesic, somnifacient, and tranquilizing, are grouped separately. Application of the term “anesthetic” to denote substances of plant or synthetic origin that are narcotics—morphine, oxycodone, Trimeperidin. for instance—was determined by convention, as was the use of the term “narcotic” to convey the sense of “anesthetic.” The main requirements of an anesthetic are that it have broad action, that is, a significant range between the effective (anesthetic) and toxic doses; that it not produce complications; and that it have no aftereffects.

Anesthetics are classified as either inhalation or noninhalation, depending on the method of administration. Inhalation anesthetics are divided into volatile anesthetics, which include ethers, chloroform, trichloroethylene, halothane, and ethyl chloride, and into gaseous anesthetics, such as nitrous oxide and cyclopropane. Noninhalation anesthetics, for example, hexobarbital, sodium thiopental, and propanilid, are administered intravenously. Narcolan is introduced by rectum.

Often, a combination of anesthetics is used to weaken or completely compensate for any negative properties that one of the ingredients might have when used alone. Surgical procedures that involve certain physiological functions can require a combination of an anesthetic with other types of agents, such as muscle relaxants, antihistamines, cholinergic and adrenergic blocking agents, ganglioplegic agents, neuroleptics, and tranquilizers. A new kind of anesthesia has been developed, neuroleptoanalgesia, in which anesthesia is brought about using neuroleptics and analgesics without the use of anesthetics.


Zakusov, V. V. Farmakologiia nervnoi sistemy. Leningrad, 1953.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.

What does it mean when you dream about an anesthetic?

To dream of being anaesthetized may represent the residue of a memory (e.g., from a medical operation). It could also reflect a desire to be relieved of some painful experience—physical, mental, or emotional.

The Dream Encyclopedia, Second Edition © 2009 Visible Ink Press®. All rights reserved.


A drug, such as ether, that produces loss of sensibility.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The analgesic effect of subarachnoid administration of tetracaine combined with low dose of morphine or nalbuphine for spinal anesthesia.
Dose-related prolongation of hyperbaric tetracaine spinal anaesthesia by clonidine in humans.
Four types of local anesthetics have been reported to cause methemoglobinemia; prilocaine, benzocaine, lidocaine, and tetracaine. It is well known that ortho-toluidine, a metabolite of prilocaine, leads to Hb oxidation (6,7).
The first substance used was chloroform, later, boiling water, glycerol, phenol, high concentrations of tetracaine and streptomycine were also used9.
Procaine, mepivacaine, lidocaine, ropivacaine, oxybuprocaine, tetracaine, bupivacaine, T-caine and dibucaine are local anesthetics that were reported [16] to be simultaneously detected by a high-performance liquid chromatography-tandem mass spectrometry method.
Homatrophine two per cent, which has been out of stock since September 2018, Tetracycline one per cent ointment which ran out first week of February 2019 and Tetracaine 0.5 per cent eye drops which has been out of stock for more than six months.
Pliaglis contains lidocaine and tetracaine (7%/7%) and utilises the proprietary phase-changing topical cream "Peel" technology.
The eyes were topically anesthetized with 0.1% tetracaine hydrochloride with 0.4% oxybuprocaine hydrochloride (double anesthetic Colicursi; Alcon Cusi, SA, Barcelona, Spain), with 3 drops spaced 30 seconds apart applied on each eye.
3-days postintratracheal application of 0.5, 1 and 2% etidocaine and 0.25, 0.5, and 1% tetracaine swelling in the axon and myelin layers and accumulation of macrophages were observed.
Topical anesthetics used include topical benzocaine 14% and tetracaine hydrochloride 2%.
Briefly, 2% lignocaine or 1% tetracaine was topically administered to the airway with or without maximum 2 mg midazolam (0.5 mg each time) and maximum 100ug fentanyl (20ug each time) given intravenously based on the assessment of the care team.
In brief, the airway was topically anesthetized with 2% lignocaine or 1% tetracaine. Midazolam (0.5 mg incrementally to a maximum of 2.0 mg) and fentanyl (20 [micro]g incrementally to a maximum of 100 [micro]g) were titrated based on the assessment of the care team [Figure 1].