Disulfiram

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Related to tetraethylthiuram disulfide: tetramethylthiuram disulfide

disulfiram

[di′səl·fə‚ram]
(pharmacology)
C10H20N2S4 A drug used to treat alcohol abuse that blocks the metabolism of acetaldehyde, the major metabolite of ethanol, causing a rapid buildup of acetaldehyde and a severe physiological syndrome intended to prevent or modify further immediate drinking behavior. Also known as Antabuse.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Disulfiram

 

(also teturamin, Antabuse), a drug used to treat alcoholism. Disulfiram inhibits the oxidation of alcohol, causing acetic aldehyde to accumulate. As a result, the consumption of alcohol leads to such symptoms as sensation of heat, tightness in the chest, heart palpitations, anxiety, and vomiting. Disulfiram is taken orally in the form of tablets. Treatment is first undertaken in a hospital.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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