tetrodotoxin


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tetrodotoxin

[¦te·trə·dō′täk·sən]
(biochemistry)
C11H17N3O8 A toxin that blocks the action potential in the nerve impulse.
References in periodicals archive ?
Tetrodotoxin (TTX) was extracted from the gonads of Puffer fish Lagocephalus lunaris obtained from the Red Sea.
This finding agreed with our previous study in which we showed that the pro-secretory effect of 512 [micro]g/ml STW 5 was reduced by tetrodotoxin (Krueger et al.
In contrast, block of neuronal activity with tetrodotoxin (TTX) increases the Ntype fraction to 87%.
Tetrodotoxin blocks voltage-gated sodium channels, preventing the propagation of action potentials and inducing paralysis in susceptible animals.
One can mention here the gland secretions of the bouga toad (50 to 100 times more powerful than digitalis, and containing a hallucinogen), millipedes, tarantulas, skins of poisonous tree frogs, seeds and leaves from poisonous plnants, human remains, four species of puffer fish with a significant content of tetrodotoxin.
On June 13, 2014, two patients went to the Hennepin County Medical Center Emergency Department in Minneapolis, Minnesota, with symptoms suggestive of tetrodotoxin poisoning (i.
In this series of 26 cases, samples of the suspected seafood in 21 cases were tested by the CDC or the US Food and Drug Administration (FDA) as negative for the following known aquatic toxins: ciguatoxin, saxitoxin, brevetoxin, tetrodotoxin, palytoxin, domoic acid, okadaic acid, and two blue-green algal or cyanobacterial toxins (microcystin and nodularin).
There is rumored to be a powerful drug made from Tetrodotoxin, an immensely poisonous compound derived from the puffer fish, combined with a dissociative drug called Datura, itself also a natural product.
Fish-derived tetrodotoxin was initially focused on indication of opiate addiction withdrawal but is found to have an analgesic action as well.
22] Coencapsulation of tetrodotoxin (TTX) in controlled-release devices containing bupivacaine and dexamethasone resulted in exceedingly prolonged nerve blocks.
The toxin in puffer fish, Tetrodotoxin, comes from its gallbladder, and if cut up incorrectly, the organ will release its deadly poison.
Tetrodotoxin is most likely the "ingredient" in the zombie powder "fully capable of pharmacologically inducing the prerequisite state of apparent death" (Davis, 1988, p.