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A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.



(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

References in periodicals archive ?
Saqib Ansari said recommendations have been forwarded to the government to make mandatory that birth certificates are issued only to children whose thalassanemia status has been ascertained, so must be the condition for kids seeking admissions to schools while each nikhahkhawan must be obliged to ask for thalassemia free certificate from both bride and groom before solemnizing nikah.