Thalassemia

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thalassemia

[‚thal·ə′sē·mē·ə]
(medicine)
A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.

Thalassemia

 

(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

References in periodicals archive ?
Fortunately, in the case of these children their body responded very positively to the transplant and that has helped us to cure them of thalassemia major.
Clinicoinvestigational and demographic profile of children with thalassemia major.
Endocrine complications in patients of beta thalassemia major in a tertiary care hospital in Pakistan.
2) are the common co-inherited deletions found in beta thalassemia major patients.
The effects of erythropoetic activity and iron burden on hepcidin expression in patients with thalassemia major.
p in this equation report the normal population, q stands for the homozygotes (also referred to as thalassemia major patients), whereas, 2pq report the number of heterozygotes i.
Table-I: Description of thyroid function status, age and number of transfusions in thalassemia major patients (n=56).
37 % in multi-transfused beta thalassemia major patients [8] [Table 3].
of Cases % Hereditary Haemolytic Anaemia Thalassemia Major 12 23.
The Pakistan Institute of Medical Sciences (PIMS) has diagnosed around 160 new cases of thalassemia major during four years (2008-2012).
Apart from the rare dominant forms, subjects with thalassemia major are homozygotes or compound heterozygotes for beta0 or [beta.
The only known cure for Beta Thalassemia Major is a stem cell transplant.