Molecules were developed keeping thiazole
as the template.
Other compounds activated only the p53 pathway--including niclosamide, rafoxanide, and chlorfenapyr--or the Nrf2/ARE pathway--including pinacyanol, 1,8-dihydroxy-4, 5-dinitroanthraquinone, 2-aminoanthraquinone, 2-hydrazino-4-(4-aminophenyl) thiazole
, 2-hydrazino-4-(4-nitrophenyl)thiazole, and 2-hydrazino-4-phenylthiazole (Table 2).
Weyhermuller et al., "Novel mononuclear Cu (II) terpyridine complexes: Impact of fused ring thiophene and thiazole
head groups towards DNA/BSA interaction, cleavage and antiproliferative activity on HepG2 and triple negative CAL-51 cell line," European Journal of Medicinal Chemistry, vol.
Corsini, "Synthesis, structural characterization, solution chemistry, and preliminary biological studies of the ruthenium(III) complexes [TzH][trans-Ru[Cl.sub.4][(Tz).sub.2]] and [TzH] [trans-Ru[Cl.sub.4](DMSO)(Tz)] x (DMSO), the thiazole
analogues of antitumor ICR and NAMI-A," Inorganic Chemistry, vol.
Gabellini et al., "The thiazole
derivative CPTH6 impairs autophagy," Cell Death & Disease, vol.
derivatives have potential against neurodiseases in the new drug development studies .
In addition, a recently developed methodology is applied which uses induced circular dichroism spectral profiles of G-quadruplex-ligand (Thiazole
Orange) complexes to determine if G-rich sequences can adopt G-quadruplex structure.
For example, the given thiazolidenediones definition does not make clear whether non-insulin sensitizing agents with two keto oxygens and a thiazole
group are thiazolidenediones.
Synthesis of some new Schiff bases containing thiazole
and oxazole nuelei and their fungieidal aetivity.
2-Aminothiazoles and their derivatives are well-known because of their wide spectrum of biological activity shown by the thiazole
Reticulated platelets (RP) were identified by the thiazole
orange method : 10 [micro]l of PRP was incubated with 390 [micro]l of thiazole
orange (Retic-Count; BD Biosciences) or PBS as control and anti-CD41 at room temperature for 10 minutes, in the dark.
This assay kit employs a thiazole
salt for the detection of superoxide anions by producing a colored product.