thiobarbiturate

[¦thī·ō·bär′bich·ə‚rāt]

(pharmacology)

A derivative of thiobarbituric acid that differs from the barbiturates in the replacement of one oxygen atom by sulfur but resembles the barbiturates in its effects.

Mentioned in ?

thiobarbituric acid

References in periodicals archive ?

Thiobarbiturates are useful intermediates in synthesis of heterocyclic compounds [2].

Synthesis and Biological Evaluation of Some Newly Synthesized Barbiturates and Their Derivatives by Using Task Specific Ionic Liquid [Bmim]OH

Table-1: Antioxidant/DPPH radical scavenging activity of 5-arylidene barbiturates and thiobarbiturates based derivatives

A Facile Single Pot Synthesis of Highly Functionalized Tricyclic Heterocycle Compounds via Sequential Knoevenagel-Michael Addition and their [alpha]-Glucosidase Inhibition, Antioxidants and Antibacterial Studies

This assay interference could be reproduced with thiopental added to control plasma and also with thiamylal (another thiobarbiturate) added to control plasma.

Thiobarbiturates interfere with the Dade Behring aca ammonia test

Thiourea and urea res idues containing thiobarbiturate and barbiturate analogs , res pectively, fas cinated s ubs tantial interes t due to their divers e biological activities like inhibition of collagenas e -3 (MMP-3) [10], matrix metalloproteinas es [11], and recombinant cytochrome P450 enzymes [12], methionine aminopeptidas e-1 (MetAP-1) [13].

5-Arylidene N,N-dimethylbarbiturates as Urease Inhibitors

Application of the thiobarbiturate assay to the measurement of lipid peroxidation products in microsomes.

Direct method for quantification of free malondialdehyde with high-performance capillary electrophoresis in biological samples

"The only well-documented, breed-specific anesthetic drug concern is with the use of thiobarbiturates in Greyhounds," Dr.

Going under: what you should know about anesthesia before you schedule your dog's veterinary procedure

Scharfe et al., "Binding free energy calculations and biological testing of novel thiobarbiturates as inhibitors of the human NA[D.sup.+] dependent histone deacetylase Sirt2," MedChemComm, vol.

Binding energy calculation of Patchouli alcohol isomer cyclooxygenase complexes suggested as COX-1/COX-2 selective inhibitor

As a result of pioneering work of Qin Yan, a novel series of 5-benzylidene thiobarbiturates (141) derivatives have been synthesized and screened for their antibacterial activity.