thiosemicarbazone


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thiosemicarbazone

[¦thī·ō‚sem·i′kär·bə‚zōn]
(pharmacology)
A class of chemical compounds used in treating tuberculosis; the most prominent member of the group is para-acetamidobenzaldehyde thiosemicarbazone.
References in periodicals archive ?
DNA, protein binding, cytotoxicity, cellular uptake and antibacterial activities of new palladium(II) complexes of thiosemicarbazone ligands: effects of substitution on biological activity.
Jain, "Synthesis, spectral studies and antimicrobial screening of some transition metal complexes with substituted acetophenone thiosemicarbazone," International Journal of Pharmaceutical Sciences and Research, vol.
Thiosemicarbazone (3) was obtained from a solution of equimolar amounts of acetophenone 1 and thiosemicarbazide (2) in methanol, with constant stirring for 7 hours at 65 [degrees]C and pH 4.0.
B., Capacchi, S., Bisceglie, F., Pelosi, G.; Tarasconi, P., Synthesis and characterization of square planar nickel (II) complexes with p-fluorobenzaldehyde thiosemicarbazone derivatives.
Ueda-Nakamura et al., "Benzaldehyde thiosemicarbazone derived from limonene complexed with copper induced mitochondrial dysfunction in Leishmania amazonensis," PLoS ONE, vol.
Falzirolli et al., "Cell death and ultrastructural alterations in Leishmania amazonensis caused by new compound 4-Nitrobenzaldehyde thiosemicarbazone derived from S-limonene," BMC Microbiology, vol.
Ramesh, "Catalytic application of dinuclear palladium(II) bis(thiosemicarbazone) complex in the Mizoroki-Heck reaction," Tetrahedron Letters, vol.
(2001) Platinum(II) complexes with 2-acetyl pyridine thiosemicarbazone. Synthesis, crystal structure, spectral properties, antimicrobial and antitumour activity.
Rajamand, "Preparation and biodistribution studies of a radiogallium-acetylacetonate bis (thiosemicarbazone) complex in tumor-bearing rodents," Iranian Journal of Pharmaceutical Research, vol.
The 3-aryl-4(3H)-quinazolinone-2 carboxaldehydes, their corresponding Schiff's base, and thiosemicarbazone derivatives reported (80-82) as anticonvulsants [75] (see Scheme 61).