Our results established a preliminary MED and threshold dose
for vitamin D photosynthesis in budgerigars.
Even if the single hit theory is not the mechanism, available evidence suggests that the threshold dose
required for mesothelioma is quite low.
* Deterministic effects are those in which the severity of the effect, rather than the probability, increases with increasing dose and for which there is a threshold dose
. Below this threshold no effect is observed; however, at the threshold dose
, the effect occurs and the severity of the effect increases as the dose increases.
Reactions were elicited at widely varying threshold doses
ranging from 100 [micro]g to 1 g of peanut protein.
The threshold dose
for a specific deterministic effect depends on the type of radiation, on the dose-rate pattern over time (i.e., dose-rate history), and possibly other factors.
Instillation of six different ultrafine carbon particles indicates a surface area threshold dose
for acute lung inflammation in mice.
First of all, there is no guarantee that a threshold dose
will exist for a particular apical response.
Also known as deterministic effects, nonstochastic effects are associated with a threshold dose
and increase in severity as the dose increases.
These distributions are combined into an overall log-normal distribution for the threshold dose
(dose below which there is no contribution to a toxic response) by assuming the variables act independently and multiplicatively.
Employing such approaches can cause one to conclude that an LNT-type dose-response curve is real when actually there is a reduced risk at low doses and dose rates and/or a threshold dose
for excess risk.
Probability increases linearly with increasing dose, and there is no threshold dose
for these effects.
This dose is approximately 20% lower than the threshold dose
previously calculated using the SCR approach on each individual dose-effect data set (Wolansky et al.