Thymidylic Acid

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Related to thymine nucleotide: adenine nucleotide

thymidylic acid

[¦thī·mə¦dil·ik ′as·əd]
(biochemistry)
C10H15N2O8P A mononucleotide component of deoxyribonucleic acid which yields thymine,D-ribose, and phosphoric acid on complete hydrolysis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Thymidylic Acid

 

a complex natural compound. Thymidylic acid is a mononucleotide consisting of the pyrimydine base thymine, the carbohydrate deoxyribose, and a phosphoric acid residue. The compound takes the form of fine acicular crystals that are readily soluble in water; its molecular weight is 322.2. Thymidylic acid is contained in all living cells as a component of deoxyribonucleic acid (DNA). It is formed by methylation of deoxyuridylic acid. By adding two phosphoric acid residues, thymidylic acid becomes thymidine triphosphoric acid (TTP), which, under the action of the enzyme DNA-polymerase, becomes part of the growing polynucleotide DNA chain.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.