thymol


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thymol

a white crystalline substance with an aromatic odour, obtained from the oil of thyme and used as a fungicide, antiseptic, and anthelmintic and in perfumery and embalming; 2-isopropylphenol. Formula: (CH3)2CHC6H3(CH3)OH

Thymol

 

(5-methyl–2-isopropyl-l-phenol), a colorless crystalline substance with a specific odor and sharp taste; soluble in organic solvents but not in water. Melting point, 51.5°C; boiling point, 232.9°C.

Thymol exhibits all the reactions characteristic of phenols. It is found in certain essential oils, such as thyme oil (from Thymus vulgaris, from which it takes its name), in which its content is 20–50 percent, and thyme, from which it may be separated by rectification.

Thymol is produced on an industrial scale by the reaction of m-cresol, CH3C6H4OH, with propylene, CH3—CH═CH2. It is used as a raw material in the production of menthol and such indicators as thymolphthalein and thymol blue. It is used in medicine as an anthelmintic in the treatment of ancylostomiasis, trichuriasis, and some other helminthiases, as an antiseptic for the mouth, throat, and nasopharynx, in dentristry to anesthetize dentin, and in the pharmaceutical industry as a preservative. The use of thymol as an anthelmintic is contraindicated in cases of pregnancy, cardiac insufficiency, liver and kidney diseases, and peptic ulcer.

thymol

[thī‚mȯl]
(organic chemistry)
C10H14O A naturally occurring crystalline phenol obtained from thyme or thyme oil, melting at 515°C; used to kill parasites in herbaria, to preserve anatomical specimens, and in medicine as a topical antifungal agent. Also known as thyme camphor.
References in periodicals archive ?
Within the chemical composition of EOs, mainly carvacrol and thymol show antibiofilm activity [13].
According to the manufacturer, the main constituents in the EOM were cinnamaldehyde, thymol, and eugenol.
Plant 15 was the only one to present thymol as the main compound (47.5 %) and it presented a low content of carvacrol (3.2 %).
This study was aimed to use scC[O.sub.2] for preparation of chitosan, methacrylic and itaconic acid aerogels and their further impregnation with thymol. The gels were prepared by free radical copolymerization of methacrylic and itaconic acid in the presence of chitosan [39] and were converted to the alcogels.
Content data and relative content of thymol were submitted to analysis of variance, and the quantitative values of drying temperatures were submitted to regression analysis with linear and quadratic coefficients using the statistical program Sisvar (FERREIRA, 2011).
The scientists prepared a first group of emulsions from an oil phase using 0.1% to 20% thymol in hexane.
Thymol, linalool, and citronellol were obtained, along with technical product information (Table 1), from Quinari[R], which produces and sells essential oils and derivatives on an industrial scale.
Furthermore, phenol made up 0.6% of the concentrated product 2, thymol 1.10% and naphthols 3.32%.
Results demonstrated that supplementation with thymol and isoeugenol increased female triglycerides compared to males and to control females.
[5] demonstrated that eugenol, carvacrol, thymol, and cinnamaldehyde are the main components of EO, which provide antifungal and antioxidant activities.
Carvacrol (5-isopropyl-2-methylphenol) and thymol (2-isopropyl-5-methylphenol) are the major components of the essential oils of some species belonging to the Lamiaceae family including oregano, and these are phenolic compounds; isomers of monoterpenes exhibit significant antimicrobial activity in vitro [6, 7].