tophus

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Related to tophaceous: tophaceous gout

tophus

[′tō·fəs]
(medicine)
A localized swelling principally in cartilage and connective tissues in or adjacent to the small joints of the hands and feet; occurs specifically in gout.
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It has been licensed by the US Food and Drug Administration (FDA) for refractory tophaceous gout.
All tophaceous deposits were dissected, taking special care not to damage the skin.
Focal calcifications around joints similar to tophaceous gout may be also seen in patients with pseudogout (Figure 5).
2-4) Tophaceous gout, however, occurs in less than 10% of cases.
Tophaceous gout of the spine in a patient with no peripheral tophi: case report and review of the literature.
20 Years, N, 2013 and 2023 60 Figure 12: 6MM, Tophaceous Gout Cases in the Diagnosed Prevalent Population of Gout, Both Sexes, Ages?
However, if the patient has moderate tophaceous gout or chronic gouty arthropathy, it's appropriate to place the patient on pegloticase (Krystexxa) while discontinuing all other urate-lowering agents.
Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout.
There were multiple small nodules and a large nodule on the dorsum of left hand at the base of 3rd metacarpal (Figure 1), a localized cystic granuloma in the retrocalcaneal region is shown, and multiple tophaceous deposits over the 1st metatarsophalangeal joint and hallux valgus deformity are seen.
3SBio's pegsiticase has shown a promising efficacy and safety profile in early clinical trials and Selecta and 3SBio plan to advance clinical studies of pegsiticase-based treatments for refractory and tophaceous gout as well as tumor lysis syndrome
They applied the ACR working case scenarios and grouped patients by increasing level of disease severity Patients in the scenarios 1-3 group had intermittent symptoms and no tophi (mild disease); patients in the scenarios 4-6 group had intermittent symptoms and 1 tophus or more (moderate disease), and patients in the scenarios 79 group had chronic tophaceous gouty arthropathy (more severe disease).