microbicide

(redirected from Topical microbicide)
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microbicide

[mī′krō·bə‚sīd]
(materials)
An agent that kills microbes.
References in periodicals archive ?
Patient compliance will determine the success of any therapeutic intervention, including a topical microbicide, as recent clinical trials testing the efficacy of tenofovir-based gels have demonstrated [80, 83].
The application of topical microbicides for the prevention of genital herpes infection was described recently (Keller et al., 2005).
(16) Within the next few years, however, there may be a host of new weapons to fight STD transmission, including vaccines against chlamydia, HPV, genital herpes, gonorrhea and HIV, (12) and virus- and bacteria-killing gels, foams, creams or films, known collectively as topical microbicides. (13) STDs At-A-Glance STD Type Estimated Prevalence & Incidence Symptoms * HPV (viral) Human papillomavirus infection (HPV) - 20 million people may cause genital warts, but currently infected generally doesn't cause symptoms.
VivaGel is a topical microbicide gel product that has been developed for women as a preventative against the sexual transmission of HIV.
Phase I trial of the topical microbicide BufferGel: safety results from four international sites.
(10.) van de Wijgert J et al., Phase 1 trial of the topical microbicide BufferGel[TM]: safety results from four international sites, Journal of AIDS, 2001, 26(1):21-27.
Although topical microbicides, which are substances like gels, films or suppositories, can kill or neutralize viruses and bacteria, it is recommended they be used along with condoms.
Inhibition of Neisseria gonorrhoeae genital tract infection by leading candidate topical microbicides in a mouse model.
The new tools for HIV prevention currently under development include vaccines, topical microbicides such as gels, creams and foams that can be applied to the vagina or rectum prior to sexual intercourse.
Topical microbicides are products that may be formulated as gels, sponges, films, or rings that can be applied to vaginal or rectal mucosa with the goal of preventing or significantly reducing the risk of acquiring STIs, including HIV (Stein 1990).
My own research focuses on behavioral issues related to acceptability and acceptance of vaccines and topical microbicides for the prevention of HIV and other STDs.
As rapid or uncontrolled emergence of HIV drug resistance (HIVDR) is widely feared as a potential consequence of ART scale up, causing failure of ART programme, prevention through PEP and topical microbicides, evaluation of emerging HIVDR is highly recommended along with ART schedules.