transgene


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transgene

[′tranz‚jēn]
(genetics)
Genetic material from one organism that has been experimentally transferred to another, so that the host acquires the genetic traits of the transferred genes in its chromosomal composition.
References in periodicals archive ?
These now respond as the cell would intend, signaling for the production of the gene product as, where, and when needed; the transgene product is produced, and by nature of the treated issue being recessive, this positive expression of correct gene function can replace that of the inborn defective gene.
Under the terms of the agreement Transgene will contribute both its OV design and engineering expertise, as well as its proprietary engineered Vaccinia virus, derived from its Invir.
Transgene previously reported a preclinical proof-of-concept data showing that an oncolytic Vaccinia virus encoding a sequence of anti-PD1 demonstrated better overall survival than the combination of separate single agents.
Transgene has a large collection of viral vectors and is renowned for its competence in the genome engineering of these vectors.
In this study, we examined cumate-inducible transgene expression and loxP element-mediated transgene recombination using Cre recombinase in avian cells.
The Phase 2 clinical trial will explore the potential of combining Transgenes TG4010, an investigational therapeutic vaccine designed to generate an immune response against MUC1 expressing tumors such as NSCLC, in conjunction with Bristol-Myers Squibbs immune checkpoint inhibitor, Opdivo, designed to alleviate immune suppression.
When these worms were moved back to the cooler temperature, their transgenes remained active - a sign that they were retaining the memory of their exposure to warmth.
Transgene was expressed under the control of ubiquitin promoter.
Transgene, ABL, and ABL Europe are members of the Institut MA(c)rieux.
The report provides brief overview of Transgene SA including business description, key information and facts, and its locations and subsidiaries
Microinjection that allows delivery of the transgene directly into the nucleus, Transgene is directly microinjected into the male pronuclei of fertilized eggs [1].
This report provides comprehensive information on the current therapeutic developmental pipeline of Transgene Biotek Limited's, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.