Transversion


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transversion

[trans′vər·zhən]
(cell and molecular biology)
A mutation resulting from the substitution in deoxyribonucleic acid or ribonucleic acid of a purine for a pyrimidine or a pyrimidine for a purine.

Transversion

 

in biology, a type of mutation involving replacement of the nitrogenous base in deoxyribonucleic acid (DNA). In transversion, a purine base (adenine or thymine) is replaced by a pyrimidine base (guanine or cytosine), or vice versa.

References in periodicals archive ?
The variable sites were comprised of 18 transitions and one transversion.
The electropherogram shows a thymine to adenine transversion at nucleotide position 1799 of the complementary DNA (red arrow), resulting in glutamic acid for valine substitution at amino acid position 600.
8993T>G transversion was responsible for the major phenotypic differences between the mutant and wild-type cybrids that had the same nuclear background.
Quantification of homoplasy for nucleotide transitions and transversions and a reexamination of assumptions in weighted phylogenetic analysis.
En este sentido, los individuos que presentaron el patron electroforetico D (900/1250/1300), son portadores de la transicion 1337C>T en heterocigosis y la transversion 1410G>T en homocigosis GG.
The relations between genetic distance and transition and transversion for pairwise sequence comparisons were analyzed by DAMBE (Xia, 2000).
Other nonsynonymous substitutions detected in COIII sequences were two transitions at positions 427 and 502, and a transversion at position 429.
No es casual su obsesivo retorno a la traduccion como tema cardinal de sus trabajos, parafrasis de la obra entera, tan cercano en esto a la tarea titanica de transversion linguistica de Vladimir Nabokov.
Los aductos en AFBl-N7-Gua han sido relacionados especificamente con la transversion de G:C[right arrow]T:A en la tercera base en el codon 249 (48).
About 10% of endometrioid tumors had markedly increased transversion mutations and newly identified mutations in POLE, a gene involved in nuclear DNA replication and repair.
The trimming resulted in the loss of only one SNP from the modern Chilean chickens (CHL31); a C at position 168 (relative to the reference sequence NC_01323): the remaining Chilean chickens all differed from the reference sequence at this position, with a transversion from C to T.