Transversion

(redirected from transversion mutation)
Also found in: Dictionary, Thesaurus, Medical, Legal.
Related to transversion mutation: frameshift mutation, transition mutation

transversion

[trans′vər·zhən]
(cell and molecular biology)
A mutation resulting from the substitution in deoxyribonucleic acid or ribonucleic acid of a purine for a pyrimidine or a pyrimidine for a purine.

Transversion

 

in biology, a type of mutation involving replacement of the nitrogenous base in deoxyribonucleic acid (DNA). In transversion, a purine base (adenine or thymine) is replaced by a pyrimidine base (guanine or cytosine), or vice versa.

References in periodicals archive ?
The Ratio of Transition to Transversion Mutations Is High
Is it possible to obtain an approximation of the ratio of transition to transversion mutations by examining these newly arisen substitutions?
30-34) KRAS transversion mutations in particular have been linked to smoking history in prior studies (30,35,36); among the KRAS mutations detected in our study, approximately 90% were transversions, confirming this association.