Transversion

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Related to transversion mutation: frameshift mutation, transition mutation

transversion

[trans′vər·zhən]
(cell and molecular biology)
A mutation resulting from the substitution in deoxyribonucleic acid or ribonucleic acid of a purine for a pyrimidine or a pyrimidine for a purine.

Transversion

 

in biology, a type of mutation involving replacement of the nitrogenous base in deoxyribonucleic acid (DNA). In transversion, a purine base (adenine or thymine) is replaced by a pyrimidine base (guanine or cytosine), or vice versa.

References in periodicals archive ?
Is it possible to obtain an approximation of the ratio of transition to transversion mutations by examining these newly arisen substitutions?
In addition to the large number of mutations, we found all possible base transition and base transversion mutations in OsMsh6 mutants.
Therefore, G:C>T:A or G:C>C:G transversion mutations frequently occur under oxidative conditions.
In this study, the percentage of G/C or A/T mutations detected was 4.34% (3 of 69), higher than that reported in the MITOMAP database, suggesting that transversion mutations without changes in the number of hydrogen bonds do not escape detection by TTGE.