triterpene

(redirected from triterpenoids)

triterpene

[trī′tər‚pēn]
(organic chemistry)
One of a class of compounds having molecular skeletons containing 30 carbon atoms, and theoretically composed of six isoprene units; numerous and widely distributed in nature, occurring principally in plant resins and sap; an example is ambrein.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The unrefined emollients including tocopherol, carotenoids, hydrocarbons, steroids, triterpenoids and alcohol are considered superior formulations over chemically modified emollients in emollient market .
Ibrexafungerp (formerly SCY-078), the first representative of a novel family of antifungal compounds referred to as triterpenoids, is being developed for oral and intravenous (IV) administration and is in clinical development for the treatment of both serious outpatient fungal infections, including VVC, and hospital-based life-threatening fungal infections, including invasive candidiasis (IC), invasive aspergillosis (IA) and refractory invasive fungal infections.
Ocotillol-type saponins share a tetrahydrofuran ring as the tetracyclic triterpenoids, which is rare existing in Panax quinquefolius L., Panax japonicus, Hana mina, and Vietnamese ginseng [1].
Centella asiatica (also known as gotu kola) is another plant that depends upon secondary metabolites called triterpenoids to thrive in the different climate zones of subtropical and tropical regions.
[13] Phytochemical screening of the plant extract showed the presence of alkaloids, flavonoids, sterols, carbohydrates, and triterpenoids. High-performance liquid chromatography analysis revealed that flavones-c glycosides are present in the plant.
SCYNEXIS provided a year-end update and 2019 development plans for ibrexafungerp, an investigational antifungal agent and the first representative of a novel class of structurally-distinct glucan synthase inhibitors, triterpenoids. "In 2018, we achieved multiple meaningful clinical milestones, most notably reporting positive data from our Phase 2b DOVE study evaluating oral ibrexafungerp for the treatment of vulvovaginal candidiasis," said Marco Taglietti, M.D., President and CEO of SCYNEXIS.
Other triterpenoids were found in several Scorzonera species (Table 3).
SCY-078 is the first representative of a novel class of structurally-distinct glucan synthase inhibitors, triterpenoids.
[15] Lemon seeds are rich in triterpenoids [16] and they have hypolipidaemic, anti-obesity, anti-hyperglycaemic and anti-cancerous effect.
At present triterpenoids and phytosterols are separated from methanolic extracts in different plant parts (fruit, stem, leaf, and root) in S.
Similarly, the problem of absorbance also occurred during the determination of compounds in Centella extracts, in which the extracts generally have many colour reagents of triterpenoids, sapogenins, and saponins [26].
Testa, "Triterpenoids as new promising anticancer drugs," Anticancer Drugs, vol.