Trophoblast

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trophoblast

[′träf·ə‚blast]
(embryology)
A layer of ectodermal epithelium covering the outer surface of the chorion and chorionic villi of many mammals.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Trophoblast

 

the exterior layer of cells in the embryos of mammals. The trophoblast is isolated in the blastocyst stage and makes possible contact between the embryo and the mother’s system by allowing nutrients to pass from the mother to the embryo. The part of the trophoblast located above the embryonic shield is called Rauber’s layer. The trophoblast that is lined internally with mesenchymal cells is called the chorion. The trophoblast plays a role in the implantation of the embryo in the uterine wall and the formation of the placenta.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole.
Clinical management and the neoplastic sequelae of trophoblastic embolization associated with hydatidiform mole.
Vascular resistance index (RI) was 0/37 and the sinologist suggested placental site trophoblastic tumor.
Gestational trophoblastic disease is a group of disorders caused by the overgrowth of placental tissue and is defined as the spectrum of disease that has at one extreme the benign hydatidiform mole which could be complete or partial mole, the locally Invasive mole, Placental site trophoblastic tumor, Gestational tropho-blastic neoplasia and at the other end, the highly malignant Choriocarcinoma, based on genetic and histopathological features1.
Furthermore, attenuated expression of HAPLNs in malignant gliomas (38) results in similar characteristics with trophoblastic invasion, suggesting that HAPLNs are an important factor for normal placentation, which failures in PE.
Expression of the proliferation marker Ki-67 and of p53 tumor protein in trophoblastic tissue of preeclamptic, HELLP, and intrauterine growth-restricted pregnancies.
Eradication of the molar tissues is the best way to reduce the risk of postmolar gestational trophoblastic diseases.
Deficient trophoblastic invasion of the maternal tissue can lead to pregnancy complications, such as IUGR and preeclampsia, while excessive invasion can lead to MAP, such as PP (14).
Of complete moles, 15-20% will continue on to develop gestational trophoblastic neoplasia, whereas <5% of partial moles do.
However, data from the literature indicate that ART does not seem to influence the development of gestational trophoblastic neoplasia after hydatidiform moles [24, 26].
The chorionic villi were large and cellular, with convoluted outlines and presence of both trophoblastic pseudoinclusions (Figure 2(c)), secondary to villous scalloping, and focal robust ferrugination of the basal lamina (Figure 2(c)), highlighted by iron stain (Figure 2(d)).