tumors of the testis: the widening spectrum of trophoblastic
disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic
disease, and management of hydatidiform mole.
Clinical management and the neoplastic sequelae of trophoblastic
embolization associated with hydatidiform mole.
Vascular resistance index (RI) was 0/37 and the sinologist suggested placental site trophoblastic
disease is a group of disorders caused by the overgrowth of placental tissue and is defined as the spectrum of disease that has at one extreme the benign hydatidiform mole which could be complete or partial mole, the locally Invasive mole, Placental site trophoblastic
tumor, Gestational tropho-blastic neoplasia and at the other end, the highly malignant Choriocarcinoma, based on genetic and histopathological features1.
Furthermore, attenuated expression of HAPLNs in malignant gliomas (38) results in similar characteristics with trophoblastic
invasion, suggesting that HAPLNs are an important factor for normal placentation, which failures in PE.
Expression of the proliferation marker Ki-67 and of p53 tumor protein in trophoblastic
tissue of preeclamptic, HELLP, and intrauterine growth-restricted pregnancies.
Eradication of the molar tissues is the best way to reduce the risk of postmolar gestational trophoblastic
invasion of the maternal tissue can lead to pregnancy complications, such as IUGR and preeclampsia, while excessive invasion can lead to MAP, such as PP (14).
Of complete moles, 15-20% will continue on to develop gestational trophoblastic
neoplasia, whereas <5% of partial moles do.
However, data from the literature indicate that ART does not seem to influence the development of gestational trophoblastic
neoplasia after hydatidiform moles [24, 26].
The chorionic villi were large and cellular, with convoluted outlines and presence of both trophoblastic
pseudoinclusions (Figure 2(c)), secondary to villous scalloping, and focal robust ferrugination of the basal lamina (Figure 2(c)), highlighted by iron stain (Figure 2(d)).