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Related to trypsogen: trypsinogen


The zymogen of trypsin, secreted in the pancreatic juice. Also known as protrypsin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an inactive precursor (proenzyme) of the proteolytic enzyme trypsin. Trypsinogen is synthesized in the pancreas and converted into trypsin—the active enzyme—in the small intestine. The activation of trypsinogen entails the cleavage of a short peptide fragment from the N-terminal of the trypsinogen molecule by the enzyme enterokinase or by trypsin itself.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.