Granuloma

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granuloma

[‚gran·yə′lō·mə]
(medicine)
A discrete nodular lesion of inflammatory tissue in which granulation is significant.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Granuloma

 

a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Another study conducted by Dhar et al6 in 2002 in India as also reported tuberculous granuloma as the commonest 77.7% followed by sarcoidal granuloma in 13.7 and suppurative granuloma in 9%.
Tuberculous granuloma, the most common microscopic finding in cases of GITB reported by various authors ranged from 67.5% to 100% cases.
Staphylococcus epidermidis was found in one patient; pathologic examination revealed a tuberculous granuloma. Actinomyces was found in the mastoid mucosa of one patient.
Presence of well- formed tuberculous granulomas accompanied more often by Langhans giant cells, or foreign body-like granulomas in the reticular dermis.
In the reproductive age, tuberculous granulomas have to regenerate from the basal layer after menstrual shedding of the functionalis layer.
The fine structure of sarcoid and tuberculous granulomas. Postgrad Med 1970; 46:496-500.
The histologic appearance of tuberculous granulomas may be indistinguishable from those of nontuberculous mycobacterial infection.
Distribution of IFN-gamma, IL-4 and TNF-alpha protein and CD8 T cells producing IL-12p40 mRNA in human lung tuberculous granulomas. Immunology, 105(3):325-35, 2002.
At autopsy, multiple tuberculous granulomas were found (5).
Children who develop miliary TB exhibit fever, anorexia, failure to thrive, and, often, hepatomegaly indicating tuberculous granulomas on the liver.