Furthermore, the combination of p53, Ki-67, and [beta]-catenin could be a practical immunohistochemical panel to help distinguish DALM lesions from sporadic tubular adenomas
A multivariate analysis that controlled for smoking, age, and other potentially confounding factors explored differences in significant colorectal neoplasia (villous tissue, high-grade dysplasia, large tubular adenomas
, or more than two adenomas of any size) in 68 regular white-wine drinkers, 176 regular red-wine drinkers, and 1,381 abstainers (or infrequent wine drinkers).
Low levels of apoptosis and proliferative activity in colorectal villous tumors: comparison with tubular adenomas
There is some epidemiologic evidence that patients with one or two tubular adenomas
have a lower risk of progressing to cancer than patients with more adenomas.
Of the recurrent neoplasms detected in the 3-year follow-up group, 79% were tubular adenomas
, as were 80% of those found with 5-year surveillance.
In a landmark multicenter Veterans Affairs study he led, more than 70% of patients with neoplasia had, as their worst finding, one or more small tubular adenomas