tumor necrosis factor


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Related to tumor necrosis factor: Interleukin 1

tumor necrosis factor

[¦tü·mər nə′krō·səs ‚fak·tər]
(immunology)
A monokine that induces leukocytosis, fever, weight loss, the acute-phase reaction, and necrosis of some tumors.
References in periodicals archive ?
While the mice that overexpressed only tumor necrosis factor alpha quickly developed arthritis along with significant bone and weight loss, those that also overexpressed GILZ had significantly less bone loss, Shi said.
The -238 and -308 G [right arrow] A polymorphisms of the tumor necrosis factor a gene promoter are not associated with features of the insulin resistance syndrome or altered birth weight in Danish Caucasians.
It happens that the gene controlling tumor necrosis factor is located very close to these MHC genes.
Scope - DelveInsight's report provides a Tumor Necrosis Factor Alpha (TNF-a) Agonists Landscape across the globe - The report provides drug profiles which includes product description, MOA, licensors & collaborators, technology, development partner and chemical information - Coverage of the Tumor Necrosis Factor Alpha (TNF-a) Agonists pipeline on the basis of target, MOA, route of administration, technology involved and molecule type - The report reviews key players involved in the therapeutics development for Tumor Necrosis Factor Alpha (TNF-a) Agonists and also provide company profiling - Pipeline products coverage based on various stages of development from NDA filings to discovery.
Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients.
Influence of Yersinia pseudotuberculosis outer proteins (Yops) on interleukin-12, tumor necrosis factor alpha and nitric oxide production by peritoneal macrophages.
All of the other drugs on the market or nearing approval target the other cause of inflammation, tumor necrosis factor, or TNF, Kaye said.
Rockville, MD) and University of Michigan (Ann Arbor, MI) have patented Death Domain Containing Receptor (DR3 and DR3-V1) proteins which are members of the tumor necrosis factor receptor family.
Certain cytokines (interleukin [IL]-1 and tumor necrosis factor [TNF]-[alpha], but not viral replication, correlate with cardiac inflammation and can overcome resistance to chronic myocarditis (7-9).
Immunex's Enbrel and Centocor's drugs work by blocking another compound, dubbed tumor necrosis factor, or TNF.

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