Each of the planned Phase 3 studies is expected to be powered at greater than or equal to 90% to demonstrate a 30% reduction in the percentage of subjects with clinically symptomatic respiratory illness between RTB101 and placebo using a two-sided test
of 0.05 significance.
Although the alternative shows an increased weight, we compute power under a two-sided test
. To compute power, we first convert the parameters into effect size:
Statistical analysis was carried out using Fisher's two-sided test
. Differences in blood glucose with the two methods were analysed using Wilcoxon matched pairs signed ranks test.
se": statistical significance was determined using a two-sided test
(p < .05) with standard errors that assumed independently and identically distributed errors; "cluster se": statistical significance was determined using a two-sided test
(p < .05) using standard errors that were robust to hospital-level clustering; "permutation": statistical significance was determined using two-sided permutation tests (p < .05).
For assessing the null hypothesis of equality of the underlying survival distributions of the two groups, Lin and Wang propose a two-sided test
statistic based on [T.sup.*], and we will follow that convention with [T.sub.w].
(1) (95% CI, two-sided test
) for ln-transformed data, and the II was calculated as the SD of the CVa and CVi divided by the SD of the CVb.
* p < .10, two-sided test
. ** p < .05, two-sided test
Table 1 Study Sample Summary Sample 1 Sample 2 (1987-1998) (1999-2010) Forecasts identified by DJNRS 12,802 23,408 Firms removed due to insufficient (898) (1,201) Compustat data Firms removed due to insufficient (87) (108) CRSP data Final overall sample 11,817 22,099 Table 2 Test of Hypothesis 2 Table entry is Average Management Forecast Error Deflated by Firm's Stock Price 180 Days Prior to Forecast Model: [summation] [[fe.sub.i]/n] = 0 Panel A--Management forecast error for Pre-SLUSA period forecasts (1987-1998) Mean Median Minimum Maximum Standard (t-statistic) Deviation .11 .09 (b) .0688 .1491 .0013 (2.36) (a) (a) Significant at the 0.01 level (two-sided test
Dixon's test compares the individual values obtained by a single operator or the mean values obtained by several operators, or yet differences between two results obtained by several operators; it is a two-sided test
Two different cases have been considered: Case 1 states that the two binomial parameters equal some specified value and yields a two-sided test
, whereas Case 2 states that the two parameters are simply equal to one another and yields one-sided or two-sided tests
The Washington, D.C.-based public-interest group Public Citizen says the rule should consider real-world roll dynamics rather than quasi-static testing and notes that the proposed rule ignores Congress's demand for a two-sided test