cell-mediated immunity

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cell-mediated immunity

[¦sel ¦mē·dē‚ād·əd i′myü·nəd·ē]
(immunology)
Immune responses produced by the activities of T cells rather than by immunoglobulins.
References in periodicals archive ?
Type IV hypersensitivity -- cell-mediated or delayed-type hypersensitivity -- is a T-cell mediated response.
Type IV hypersensitivity reactions to latex result in various skin eruptions, which can be immediate or delayed (Table III).
Skin Reactions to Latex Reaction Response Irritation Contact Dermatitis red, chapped hands (rapid--minutes to hours) blistering burning or itching dry skin reaction limited to contact area Allergic Contact Dermatitis (ACD)(*) eczema Type IV Hypersensitivity Reaction severe itching (delayed--6 to 48 hours) vesicles/blisters dryness cracking crusting desquamation reaction may extend beyond glove area (up the arm) (*) appearance similar to irritant contact dermatitis; difference is the extent (within or beyond glove border) of the reaction (*) chemical sensitivity falls within this type of reaction Immediate Allergic Urticaria itching Type I Hypersensitivity Reaction urticaria (immediate-minutes to 1 hour) erythema edema pruritis swelling
This condition can be difficult to diagnose and is often confused with type IV hypersensitivity reaction, eczema, herpes simplex virus (HSV), and burns, potentially leading to suspicion of child abuse.
Sensitivity to titanium is characterized by the local presence of abundant macrophages and T lymphocytes and the absence of B lymphocytes, indicating type IV hypersensitivity.