Up-and-down method | Article about up-and-down method by The Free Dictionary
up-and-down method[¦əp ən ′dau̇n ‚meth·əd]
A technique which uses a unit sequential method of testing; the level of variable at each experiment is raised or lowered depending on the outcome of the previous test.
References in periodicals archive
It was clearly mentioned in the initial study that the sample size was based on the up-and-down method
of Dixon, according to which at least six independent pairs of patients with no hypotension/hypotension (response/no response pairs) should provide reliable estimates of the minimum effective dose of vasopressor [([ED.sub.50]).sup.3].