Up-and-down method | Article about up-and-down method by The Free Dictionary
up-and-down method[¦əp ən ′dau̇n ‚meth·əd]
A technique which uses a unit sequential method of testing; the level of variable at each experiment is raised or lowered depending on the outcome of the previous test.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
It was clearly mentioned in the initial study that the sample size was based on the up-and-down method
of Dixon, according to which at least six independent pairs of patients with no hypotension/hypotension (response/no response pairs) should provide reliable estimates of the minimum effective dose of vasopressor [([ED.sub.50]).sup.3].