. Nephrol Dial Transplant 1991; 14(4): 834-9.
multicenter, double-blind, placebo-controlled phase II/III clinical trial in hemodialysis patients with severe chronic uremic pruritus
and a phase II study in patients with prurigo nodularis.
Methods: In this double-blind randomized clinical trial, 52 hemodialysis patients with uremic pruritus
referred to 5azarTeaching Hospital in Gorgan in 2013 were studied.
: a clinical study of maintenance hemodialysis patients.
UV treatment of uremic pruritus
reduces the vitamin A content of the skin.
One study found significantly less refractory uremic pruritus
at 1 and 3 months after receiving acupressure.
Describe the challenges associated with identifying and treating uremic pruritus
The company is pursuing two conditions for clinical development: prurigo nodularis and uremic pruritus
. Prurigo nodularis is a chronic pruritic dermatologic condition characterized by the presence of nodules on the skin.
Biopharmaceutical company Cara Therapeutics (NasdaqGM:CARA) said on Tuesday that it has closed enrolment under its Phase 2 proof-of-concept trial of CR845 for the treatment of uremic pruritus
(UP), a chronic systemic itch condition that can occur in patients with renal failure and is often seen in patients receiving hemodialysis.
Optimal dialysis improves uremic pruritus
. Am J Kidney Dis.
TRK-820 has been developed for treatment of severe uremic pruritus
in hemodialysis patients based on the agreement signed by the three parties on March 16, 2005, for joint development and marketing.