urokinase


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Related to urokinase: streptokinase

urokinase

[‚yu̇r·ə′kī‚nās]
(biochemistry)
An enzyme, present in human urine, that catalyzes the conversion of plasminogen to plasmin.
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References in periodicals archive ?
Simon et al., "Regulation of integrin function by the urokinase receptor," Science, vol.
Ghasemzadeh et al., "Soluble urokinase plasminogen activator receptor level is an independent predictor of the presence and severity of coronary artery disease and of future adverse events," Journal of the American Heart Association, vol.
Assoian, "Differentiation-enhanced binding of the aminoterminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes," Proceedings of the National Academy of Sciences of the United States of America, vol.
The first generation is non-specific plasminogen activators such as Streptokinase and Urokinase; the second generation is represented by t-PA such as Alteplase and Prourokinase; the third generation includes Reteplase, Tenecteplase, Nateplase, Recombinant Human Urokinase, etc.
Decreased circulating urokinase plasminogen activator receptor (uPAR) concentration in acute episodes of bipolar disorder; could it be a reflection of axonal injury?
Presumptive diagnosis of MPE was made and 1.500.000 IU of urokinase was given intravenously.
* We have used urokinase in view of the reported case experience with this agent for more than a decade.
Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries.
A promising explanation may lie in the interplay between APOL1 gene expression and circulating soluble urokinase plasminogen activator receptor (suPAR) [24].
Margheri et al., "Systemic sclerosis fibroblast inhibit in vitro angiogenesis by MMP-12-dependent cleavage of the endothelial cell urokinase receptor," The Journal of Pathology, vol.
On the day after, Urokinase was injected through the chest tube, which was clamped immediately thereafter.
Minopoli et al., "UPARANT: a urokinase receptor-derived peptide inhibitor of VEGF-driven angiogenesis with enhanced stability and in vitro and in vivo potency," Molecular Cancer Therapeutics, vol.