usnic acid


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usnic acid

[′əs·nik ′as·əd]
(biochemistry)
C18H16O7 Yellow crystals, insoluble in water, slightly soluble in alcohol and ether, melts about 198°C; found in lichens; used as an antibiotic. Also known as usninic acid.
References in periodicals archive ?
Tissue-cultures of Usnea rubescens and Ramalina yasudae and production of usnic acid in their cultures.
Amongst the compounds examined, the depside atranorin had shown substantial activity as an antiglycation agent along with divaricatic acid and usnic acid. In an another study, ethyl haematommate, ethyl orsellinate, lecanoric acid, and gyrophoric acid had shown antiglycation activity [42].
With respect to cytotoxic/anticancer activities, the isolated compounds protocetraric acid and usnic acid have demonstrated to significantly inhibit the growth of the melanoma UACC-62 and B16-F10 cell lines [56].
The mechanism of action of usnic acid is not fully elucidated.
From a series of metabolites isolated from various lichen thalli, the following compounds showed a significant increase in neurite outgrowth in Neuro2A cells, compared to that in the vehicle (1% DMSO)-treated group (75.62 [+ or -] 5.75 [micro]m), upon treatment with 5 [micro]M: atranorin (131.73 [+ or -] 6.56 [micro]m), physodic acid (137.36 [+ or -] 6.67 [micro]m) and usnic acid (129.32 [+ or -] 6.95 [micro]m).
granarius of extract and two secondary metabolites (diffractaic acid and usnic acid) of a lichen species, Usnea longissima Arc.
In previous studies performed in our laboratory, H1299 lung cancer cells were exposed to 29 [micro]M usnic acid for up to 48 hours (Mayer et al., 2005).
and Kivanc, M., 2004, The antimicrobial activity of extract of the lichen Cladonia foliaceaandits (-) Usnic acid, atranorin and fumarprotocetraic acid constituents.
Haematomma nothofagi is easily confused with the New Zealand endemic species Haematomma hilare Zahlbr., but the latter contains methyplacodiolic and usnic acids, and ascospores with 7-10 septa (Staiger & Kalb, 1995).
Included among the products that will almost surely face increased scrutiny are bitter orange, or citrus aurantium; usnic acid; and aristolochic acid.
Three weeks into taking only half the recommended (dose, Rosenthal slipped into a coma, her liver apparently destroyed by usnic acid, an ingredient in the supplement.
Deglaze includes an antibacterial cleanser containing balsam and usnic acid; a camphor-, clove- and peppermint-containing toner; a clay based mask; Crude Control hydrating emulsion; Dissector drying lotion in regular or tinted formulas and Matt Velvet Dust, a powder for oily and problem skin.