valine


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Related to valine: isoleucine, histidine, serine

valine

(văl`ēn), organic compound, one of the 22 α-amino acidsamino acid
, any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.
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 commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein. It is one of several essential amino acids needed in the diet, as the human body cannot synthesize it from simpler metabolites. Young adults need about 23 mg of this amino acid per day per kilogram (10 mg per lb) of body weight. Valine can be degraded into simpler compounds by the enzymes of the body; an inherited defect in one of the enzymes involved in this process results in a rare disorder called maple syrup urine disease. Valine contributes to the structure of proteins into which it has been incorporated by the tendency of its side chain to participate in hydrophobic interactions. The structure of valine was established in 1906, after it had been first isolated from albumin in 1879. See isoleucineisoleucine
, organic compound, one of the 20 amino acids commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein.
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Valine

 

α-aminoisovaleric acid, (CH3)2,CHCH(NH2)— COOH, one of the irreplaceable amino acids. Valine is included in proteins in the form of the L-isomer. The amount of valine in protein usually varies from 4.1 percent (horse myoglobin) to 7-8 percent (human serum albumen, milk casein) and sometimes 13-14 percent (connective-tissue elastin). The absence of valine from food makes it protein-deficient and results in a negative nitrogen balance.

valine

[′va‚lēn]
(biochemistry)
C5H11NO2 An amino acid considered essential for normal growth of animals, and biosynthesized from pyruvic acid.
References in periodicals archive ?
In summary, under the conditions of this experiment, the ileal digestibility of lysine, threonine, valine, cysteine, glycine and proline in SBM from China was greater than in SBM from Brazil.
Amino acids valine, isoleucine and leucine are known as BCAA (Branched Chain Amino Acids), and they compete with each other for absorption sites, however, we may presume that amino acid imbalance stemming from the levels of isoleucine used did not occur, and all the concentration levels evaluated met the requirements of the birds in respects to egg production.
Notably, the associations between leucine, valine, and CVD risk became nonsignificant after adjustment for diabetes, dyslipidemia, and hypertension.
From this table it also follows that the treatment of the grain increased the content of phenylalanine, histidine, valine, proline, and threonine compared with the control.
Threonine, valine, methionine, leucine, cysteine, arginine and tyrosine contents were either low or absent.
The effects of GanedenBC30 with protein were examined in a randomized, double-blind crossover clinical trial on key amino acids, including leucine (the regulator for muscle protein synthesis), isoleucine and valine (branched chain amino acids), as well as histidine, alanine, asparagines, citrulline, cystine, glutamine (a key amino acid for supporting ph balance and the immune system), methionine, ornthinine, serine, threonine, tryptophan and phenylalanine.
The visit has been followed by a lunch offered by Jean and Valine Makhlouf (exclusive agents of an important Italian clothes brand).
The findings confirmed that among people with a psychiatric diagnosis, those with the methionine ("met") variation of the gene had a higher risk of suicidal behaviour compared to those with the valine variation.
These include: arginine, isoleucine, leucine, lysine, histidine, methionine, phenylalanine, threonine, tryptophan, and valine (Igwenyi, 2008).
In this study the effect of valine with different concentrations on trichophyton mentagrophytes.
In the Journal of Nutrition, an international team of researchers report an association between an increased intake of the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine and a reduced risk of being overweight or obese.