vancomycin

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vancomycin

(văn'kōmī`sĭn), antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 resembling penicillinpenicillin,
any of a group of chemically similar substances obtained from molds of the genus Penicillium that were the first antibiotic agents to be used successfully in the treatment of bacterial infections in humans.
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 in the way it acts. It is derived from the bacterium Streptomyces orientalis, which was isolated from soil of India and Indonesia. Vancomycin destroys Gram-positive bacteria, especially staphylococci and enterococci (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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). It seems to function by inhibiting the formation of the bacterial cell wall, as does penicillin; it may also cause damage to the cell membrane. The drug is intensely irritating to tissues and is usually used only for infections where microorganisms are resistant to penicillin (see drug resistancedrug resistance,
condition in which infecting bacteria can resist the destructive effects of drugs such as antibiotics and sulfa drugs. Drug resistance has become a serious public health problem, since many disease-causing bacteria are no longer susceptible to previously
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). Vancomycin must be administered intravenously because it is not absorbed through the gastrointestinal tract. Mutant microorganisms resistant to vancomycin are rare.

vancomycin

[‚vaŋ·kə′mīs·ən]
(microbiology)
A complex antibiotic substance produced by Streptomyces orientalis; useful for treatment of severe staphylococcic infections.
References in periodicals archive ?
Vancomycin Hydrochloride for Oral Solution is administered orally for treatment of enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains) and antibiotic-associated pseudomembranous colitis caused by C.
- Danish specialty anti-infective treatments manufacturer Xellia Pharmaceuticals has launched Vancomycin Hydrochloride for Injection, USP within the United States market, the company said.
- Wilmington, Massachusetts-based prescription compounding kits developer CutisPharma has received US Food and Drug Administration approval of Firvanq (vancomycin hydrochloride) oral solution for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains, the company said.
The company said FIRVANQ (vancomycin hydrochloride) will be commercially available in 25 mg/ml and 50 mg/ml strengths in convenient 150 ml and 300 ml sizes.
Contract awarded for vancomycin hydrochloride injectable solution or powder for parenteral use 500 mg vial or ampule
Vancomycin Hydrochloride Capsules are indicated for the treatment of C.
M2 EQUITYBITES-April 14, 2015-Sagent Pharmaceuticals unveils Vancomycin Hydrochloride for Injection, USP, in 10 grams
The object of this sub-limit public contract is to provide continuous partial orders of a medicinal product containing the active substance vancomycin hydrochloride - for Na Homolce Hospital for a period of 12 calendar months.
In addition, ANI acquired Shire's approved ANDAs for the currently non-marketed products vancomycin hydrochloride injectable 500 mg, 1 gm and 10 gm (USD45m in 2013 market value, per IMS Health) and vancomycin hydrochloride oral solution 250 mg and 500 mg.

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