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Vomer with chevron-shaped patch of villiform teeth, palatines with band of similar sized villiform teeth.
Jaw dentition as described for genus; villiform teeth in triangular patch on vomer and in narrow band on palatines.
Villiform teeth in elongate oval patch on vomer; preopercle with 19 small serrae on vertical limb, 2 serrae at angle slightly enlarged.
The defining histologic features of dysplastic colorectal epithelium in IBD are analogous to those of sporadic adenomatous polyps and include (1) nuclear atypism manifested by increased nuclear to cytoplasmic ratios, crowding, and hyperchromasia; (2) cytoplasmic abnormalities suggesting altered differentiation and clonality, such as diminished or, conversely, excessive goblet cell mucin; and (3) abnormal growth patterns indicating faulty control of cellular proliferation, including glandular crowding, tubular or villiform architecture and the absence of normal base-to-surface epithelial maturation.
Ambiguous changes may include reactive crypts with unusually stratified or basophilic nuclei, superficial villiform mucosa with inadequate sampling of the basal crypts, and hyperserrated, dilated crypts.
Villiform teeth in band on premaxilla and dentary; 2-3 (1-2) rows on vomer; 2-3 rows on palatine; none on ectopterygoid, endopterygoid or basihyal.
The villiform appearance and the deep glands with reactive atypical epithelium may suggest villous adenoma and invasive adenocarcinoma: The distinction from dysplastic epithelium relies on clinical and histologic clues.
Architectural changes included "budded, branched, crowded, or irregularly shaped glands, papillary extensions into gland lumina, and villiform configuration of the surface." Nuclear or cytologic changes included "marked variation in size and shape, nuclear and/or nucleolar enlargement, increased nuclear to cytoplasmic ratio, and hyperchromatism, as well as an increased numbers of abnormal mitoses." This last criterion is peculiar since it suggests that there are a normal number of abnormal mitoses.
Most cells grew in a sheetlike pattern, although rare clefts and villiform structures were seen.
Although villiform structures were not apparent, occasional tissue clefting was seen.
Although the neoplasm contained numerous capillary-sized vessels, clefted spaces and villiform structures were not apparent.