vincristine


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Related to vincristine: cyclophosphamide, methotrexate, prednisone

vincristine

[vin′kri‚stēn]
(pharmacology)
C46H56O10N4 An alkaloid extracted from the periwinkle plant (Vinca rosea) and used, as the sulfate salt, as an antineoplastic drug. Also known as leurocristine.
References in periodicals archive ?
Treatment with the alternating regimen VAC/IE (vincristine, doxorubicin, and cyclophosphamide alternating with ifosfamide and etoposide) is a standard approach in nonmetastatic ES [8].
Kaposi's sarcoma in children: An open randomised trial of vincristine, oral etoposide and a combination of vincristine and bleomycin.
She underwent 6 cycles of doxorubicin, ifosfamide, and vincristine and is currently NED on follow-up imaging approximately 10 months after chemotherapy was initiated.
It has been demonstrated that methanolic extract, given orally, induces antinociceptive properties when tested against the development of hypernociception induced by LPS and [PGE.sub.2] (mechanical inflammatory pain), as well as neuropathic pain induced by vincristine. Results also show that L-NAME, glibenclamide, methylene blue, and naloxone significantly inhibited the antinociceptive effects elicited by Boswellia dalzielii extract when assessed in [PGE.sub.2] induced mechanical hypernociception.
The outcome of fifty-four children who received vincristine during this period was analysed.
B, Schedule of two BrdU incorporation protocols proposed to evaluate micronucleus origin: BrdU-1, wherein the pulse of BrdU occurred when the synchronized cells were in the S phase; and BrdU-2, wherein the pulse of BrdU occurred 1 h before withdrawal of vincristine. Images were obtained by laser scanning confocal microscopy.
The other drugs were doxorubicin, cisplatin, methotrexate and vincristine. They work in different ways to combat tumors.
Mr Jowet was inadvertently administered the anti-cancer drug Vincristine via his spine instead of a vein.
The patient was previously treated with vincristine and prednisone, followed by chemotherapy according to the R-CHOEP-14 protocol (3 cycles) (November 2003 through January 2004).