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Related to Warm ischemia: Renal ischemia


Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.



a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.


References in periodicals archive ?
Therefore, one of the most important aim of the urologists is to reduce warm ischemia time [10, 13].
Impact of parenchymal loss on renal function after laparoscopic partial nephrectomy under warm ischemia. World J Urol 2016;34:1629-34.
(2) Cold storage reperfusion group (CSP group): normal livers without warm ischemia, subjected to 24 h cold storage (UW solution) and subsequent 1 h ex vivo warm reperfusion.
Secondly, renorrhaphy differed between the OPN and minimally invasive cohorts along with the use of renal cooling in the OPN group compared to warm ischemia time for the minimally invasive approaches.
Pinto et al., "Laparoscopic partial nephrectomy: effect of warm ischemia on serum creatinine," Journal of Urology, vol.
In this case, the limb underwent warm ischemia time until the patient arrived at the first hospital, after which he was transferred by air to a transplant center.
Warm ischemia times extended up to 80 minutes, longer than the generally accepted 30-minute limit, she said.
The amount of renal parenchyma removed during partial nephrectomy plays a major role in the development of surgically induced chronic kidney disease (CKD-S) besides warm ischemia time (WIT).
There were significant differences in estimated blood loss (EBL; ?[sup]2 = 7.285, P = 0.026), warm ischemia time (WIT; ?[sup]2 = 13.718, P = 0.001), operation time (OT; ?[sup]2 = 6.882, P = 0.032), perioperative creatinine clearance change (PCCC; ?[sup]2 = 6.206, P = 0.045), and number of patients with complications (NPC; P = 0.002) among the three groups.
After the attenuation of the effects of cold ischemia in OLT has been a crucial approach in transplant research for a long period, warm ischemia has attracted considerable interest throughout recent years as it is known to affect predominantly parenchymal liver cells and biliary injury [50-52].
In a canine model of hepatic I/R, the expression of ICAM, VCAM, P-selectin, and E-selectin was increased after 60 minutes of warm ischemia [36].