xenograft


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xenograft

[′zēn·ə‚graft]
(immunology)
A graft performed between members of different species.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
In the xenograft, alloplastic graft 1 and alloplastic graft 2 groups, characteristics that were similar to those of the control group in new bone formation.
Efficacy of the Ethanol Injection on the Control of Subcutaneous Pancreatic Cancer Cell Mouse Xenografts. During the experiments, one mouse each in the 60% and 80% ethanol groups and two mice in the 95% ethanol group of the subcutaneous xenograft model died, which might have been due to the excessive ethanol dose.
Caption: Figure 8: Western blot analysis of HT-29 cell lysate and tissue lysate derived from HT-29 xenograft tumors.
Differently, in the first molar site, sinus floor elevation was performed by applying collagen sponges together with xenograft (Bio-Oss, Wolhusen, Switzerland) at the basal bone level and in the osteotomy site, to provide more stability to the collagen (Figure 4).
In addition, they highlight the importance of organ size match since discrepancies may ultimately be a cause of xenograft failure.
Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery.
[Figure 5] shows H and E staining as well as immunohistochemical Ki-67 characterization of CRC patient tissue, xenograft tissue, and xenograft-derived organoid sections.
On the other hand, among all innovative models and readouts, the subcutaneously implanted patient derived tumor xenograft remains the core area of preclinical in vivo models because it is easy to follow and still discovers as many drugs as more sophisticated tumor models.
Therefore, we tested the anti-tumour effect of MTE and gefitinib in resistant NSCLC xenograft tumours with K-ras mutations or EGFR L858R/T790M mutation.
In our 2010 Nature article featured here, we described a next-generation sequencing-based whole-genome study to compare 4 related genomes from a single patient: a primary triple negative breast cancer, its counterpart xenograft [or "patient-derived xenograft" (PDX)], and a brain metastasis that occurred upon disease progression, all compared with the blood-derived normal DNA.
(5, 7) However, germ cell anomalies, possibly due to DBP-related effects on Sertoli cells, have been observed in fetal rat and mouse testes as well as samples of fetal human testis xenografts (testicular tissue implanted under the skin of mice).
Materials and Methods: We tested VPA for its anti-tumor activity on the human tongue cancer (SAS) cell line in vitro and in vivo in a tumor xenograft model in mice.