Slater, An Unexpected Stereochemical Course of Dihydroimidazolium
Ylide Cycloadditions, Chem.
Bagheri, "Highly effective catalytic methods for
ylide generation from diazo compounds.
Shahraki, "1H NMR technique for kinetic investigation of equilibrium between the Z- and E-isomers in a stable phosphorus
ylide involving a 2-indolinone," Progress in Reaction Kinetics and Mechanism, vol.
[section]ahin, "Polysubstituted fused ring bicyclic thiohydantoins from aminocarbo-N-thioylpyrrolidines derived from azomethine
ylide 1,3-dipolar cycloadditions," Heterocycles, vol.
Shahraki, "[sup.1]H NMR technique for kinetic investigation of equilibrium between the Z- and E-isomers in a stable phosphorus
ylide involving a 2-indolinone," Progress in Reaction Kinetics and Mechanism, vol.
Generation of dianion (base) in the presence of phosphonium salt and concomitant formation of
ylide at sufficiently high cathodic potential as per Eq.
According to press release issued here on Monday, the title of the poster was "Highly Selective Sulphur
Ylide Mediated Asymmetric Epoxidations and Aziridinations Using an Inexpensive Chiral Sulfide; Applications to the Synthesis of Quinine and Quinidine." Quinine is a well-known anti-malarial drug and its synthesis is considered a challenging task.
According to press release issued here on Monday, the title of the poster was Highly Selective Sulfur
Ylide Mediated Asymmetric Epoxidations and Aziridinations Using an Inexpensive Chiral Sulfide; Applications to the Synthesis of Quinine and Quinidine.
The team created the
ylide (benzoylmethylene) triphenylphosphorane by ball-milling (phenacyl) triphenylphosphonium bromide with anhydrous potassium carbonate ([K.sub.2]C[O.sub.3]), a base.
Lebel and co-workers have found that Wilkinson's catalyst [[ClRh([PPh.sub.3]).sub.3]] can be used to generate the key phosphonium
ylide from [PPh.sub.3] and the diazo compound [TMSCHN.sub.2] (TMS = [SiMe.sub.3]).
PHOTO :
ylide of the structure [Mathematical Expressions Omitted].