adherens) and communicative junctions (gap junctions),
Mitchell, "Faecal levels of zonula
occludens toxin in paediatric patients with Crohn's disease and their association with the intestinal microbiota," Journal of Medical Microbiology, vol.
Esto es posible mediante la zonula
de Zinn (red de fibras elasticas ancladas al cristalino y al musculo ciliar) que se encuentra dispuesta de tal forma que cuando el musculo ciliar se contrae, las fibras se relajan y el cristalino se hace mas abombado incrementando el poder de refraccion para enfocar objetos cercanos, y con la relajacion del musculo ciliar, las fibras se tensan y el cristalino se aplana para enfocar objetos lejanos.
The structure, function, and regulation of interepithelial zonula
occludens [tight junction (TJ)] are important for intestinal barrier function.
Fasano, "Regulation of intercellular tight junctions by zonula
occludens toxin and its eukaryotic analogue zonulin," Annals of the New York Academy of Sciences, vol.
occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions," in Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, M.
Interestingly, unaltered occludin structure in the tight junctions area has been observed after metformin application as in the zonula
occludens in the duodenal endothelium secondary to hepatic steatosis due to an elevated fructose diet .
Markers for EMT include increased N-cadherin and vimentin, in addition to decreased E-cadherin, epithelial cell adhesion molecule (EpCAM), and other epithelial cell markers, which includes both cytokeratins and zonula
TJ proteins such as occludin, claudin, and zonula
occludens (ZO) play a critical role in maintaining BBB integrity and low permeability .
Antibody against zonula
occludens-1 (ZO-1) was purchased from Thermo Fisher Scientific (MA, USA).