zonula occludens


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zonula occludens

[¦zōn·yə·lə ə′klüd·ənz]
(cell and molecular biology)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development.
Regulation of intercellular tight junctions by zonula occludens toxin and its eukaryotic analogue zonulin.
Uzzau et al., "Zonula occludens toxin structure-function analysis: Identification of the fragment biologically active on tight junctions and of the zonulin receptor binding domain," Journal of Biological Chemistry, vol.
Goodenough, "Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia," The Journal of Cell Biology, vol.
Abbreviations: AFC, total alkaloid fraction extracted from the aerial parts of Fumaria capreolata: ANOVA, one-way analysis of variance; BPC, base peak chromatogram; DAD, diode array detection; DNBS, dinitrobenzenesulphonic acid; EIC, extracted ion chromatogram; ESI, electrospray ionization; GAPDH, 3-phosphate dehydrogenase; 1BD, inflammatory bowel disease; ICAM, intercellular adhesion molecule; IFN-[gamma], interferon-[gamma]; IL, interleukin; iNOS, inducible nitric oxide synthase; LC, liquid chromatography; LPS, lipopolysaccharide; MMP, metalloproteinase; MS, mass spectrometry; RT, retention time; TGF, transforming growth factor; TNF[alpha], tumour necrosis factor [alpha]: TOF, time-of-flight; ZO, zonula occludens.
Gagell et al., "Association between segments of zonula occludens proteins: live-cell FRET and mass spectrometric analysis," Annals of the New York Academy of Sciences, vol.
One of the early events in EMT is the disassembly of tight junctions, with consequent redistribution of zonula occludens (ZO) proteins, claudins, and occludin, the disruption of the polarity complex, and the initiation of cytoskeletal reorganization [64].
The 1038 bp open reading frame (ORF) encoding 346 amino acid protein was discovered in UPEC strain Z42 isolated from a prostatitis patient when searching for homologues of zonula occludens toxin among UPEC strains.
Under the zonula occludens and forming an axis in an apical-basal direction are three types of adherence junctions: zonula adherens, also known as belt desmosomes; macula adherens, or punctate desmosomes; and hemidesmosomes.
In addition, nephrin forms complexes--as proven through coimmunoprecipitation and pull-down assays--with cadherins, p120 catenin, and scaffolding proteins zonula occludens protein 1 (ZO-1), CD2AP, and calcium/calmodulin-dependent serine protein kinase (CASK) [76].
cholerae strains isolated from the environment have rarely been virulent in terms of carrying known human virulence genes such as ctx; cholera toxin, tcp; toxin-coregulated pili, and zot; zonula occludens toxin (Bauer et al.