zymogen


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Related to zymogen: zymogen granules

zymogen

[′zī·mə·jən]
(biochemistry)
The inactive precursor of an enzyme; liberates an active enzyme on reaction with an appropriate kinose. Also known as proenzyme.
References in periodicals archive ?
They confirmed experimentally in vivo and in vitro that decreasing pH (acidifying) increases the sensitivity of the acinar cells to zymogen activation.
Phenoloxidase and its zymogen from the haemolymph of larvae of the lepidopteran Spodoptera littoralis (Lepidoptera: Noctuidae).
Plasminogen which is involved in the fibrinolytis system is present in the tissue as zymogen and is activated as a result of interaction with tissue plasminogen activator (t-PA) which is also present in the tissue.
NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol.
Autoantibodies to zymogen granule glycoprotein 2 (GP2) have shown specificity for Crohn's disease and could improve the serological diagnosis of IBD.
3] and Bryostatin-1 promoted the cleavage of the zymogen of caspase-3 to yield the active form of caspase-3 in ALL cell lines after 24 hr exposure.
Acinic cell carcinoma (AcCC) is a malignant epithelial salivary gland neoplasm that demonstrates serous acinar cell differentiation with cytoplasmic zymogen secretory granules.
com)-- Plasminogen activator (PA), classified immunological into urokinase-type PA (uPA) and tissue-type PA (tPA), converts the zymogen plasminogen to the active, broad-spectrum serine protease plasmin.
Activated factor XII levels are dependent on factor XII 46C/T genotypes and factor XII zymogen levels, and are associated with vascular risk factors in patients and healthy subjects.
MMP-1 is secreted from cells as an inactive precursor of the active proteinase, zymogen (Pardo and Selman 2005).
Measurement of the size distribution of zymogen granules from rat pancreas.