Our study concludes that in our setup the incidence of Intraventricular dyssynchrony was high among patients presenting with left
bundle branch block. LV dyssynchrony is not the only mechanism responsible for less efficient LV pump but there are other mechanisms in play as well.
Complete left or right
bundle branch block at presentation has been reported to occur in 1% to 15% of patients with acute myocardial infarction and it has been associated with increased risk for short- and long-term death.
Cardiac magnetic resonance evaluation of the impact of interventricular and intraventricular dyssynchrony on cardiac ventricular systolic and diastolic function in patients with isolated left
bundle branch block. Am J Cardiol.
Hindman MC, Wagner GS, JaRo M, Atkins JM, Scheinman MM, DeSanctis RW, Hutter AH Jr, Yeatman L, Rubenfire M, Pujura C, Rubin M, Morris JJ (1978) The clinical significance of
bundle branch block complicating acute myocardial infarction.
But left
bundle branch block (LBBB) is common, especially as people get older.
Wagner, "Defining left
bundle branch block in the era of cardiac resynchronization therapy," The American Journal of Cardiology, vol.
Abnormalities, noted in patients ECGs' were as follows: ST depression (Minnesota code 4.1.2: STJ depression [greater than or equal to] 1 mm but < 2 mm and ST segment horizontal or downward sloping in any of leads V1, V2, V3, V4, V5), T-wave changes (Minnesota code 5.2: T amplitude negative or diphasic with negative phase at least 1 mm but not as deep as 5 mm in lead I or V6, or in lead aVL when R amplitude is [greater than or equal to] 5 mm), early QRS transition zone (Minnesota code 9.4.1: QRS transition zone at V3 or to the right of V3 on the chest), complete right
bundle branch block (RBBB) (Minnesota code 7.2.1), complete left
bundle branch block (LBBB) (Minnesota code 7.1.1).
Because left
bundle branch block and non-ischemic heart disease lead to diffuse, as opposed to localized, heart problems, study authors reasoned women were more responsive to CRT-D therapy, a treatment that strengthens the overall mechanical pumping action of the heart and coordinates the heart's electrical activity.
Also, a post-hoc subgroup analysis of the primary end point suggests that patients with an intrinsic QRS duration of more than 150 milliseconds derive more benefit from CRT-ICD therapy, as do those with left
bundle branch block, although the latter fending was weaker, Dr.
The new use is for patients with an abnormality known as left
bundle branch block, which occurs when there is delayed activation and contraction of the left ventricle.
Panel members said the approval should be limited to patients in those categories who also have an electrical problem in the heart known as a left
bundle branch block. Boston Scientific said about 70% of the patients it studied had that problem.
A nurse took his ECG which revealed a massive heart attack with left
bundle branch block.