70-71])), and spectinomycin was recommended only for
gonococci. Furthermore, they are intramuscular drugs and therefore less comfortable to administer than oral treatment.
[sup][4] The present study showed that in addition to
gonococci, S.
Briefly, to quantify the total number of macrophage-associated
gonococci, treated cells were washed 3-5 times to remove nonadherent bacteria and then lysed with 1% saponin (Sigma, St Louis, MO, USA) in PBS for 30 min.
(19) In the Asia-Pacific and European regions, for instance,
gonococci have been observed to need increased concentrations of antibiotics to stop them multiplying.
In three cases, although tests were negative either for TB (no high ESR), tumour (no tumour marker was positive), Chlamydia,
Gonococci, HBSAg, HCVAb, or HIVAb, however, they were fully treated after the routine therapy for Gram-negative and Gram-positive infections.
Each STI "star" namely Chlamydia, Syphilis, Hepatitis B Virus and
Gonococci gives an interview in a caustic and striking tone.
Results from this study and other studies in China had suggested that Ser91 mutation might play an important role in mediating quinolone resistance in
gonococci (24,26-27).
The farAB-encoded efflux pump mediates resistance of
gonococci to long-chained antibacterial fatty acids.
The recent emergence of quinolone resistance among
gonococci isolated in South Africa now threatens to undermine the success of the syndromic management approach to date.
In the
gonococci, the chromosomally mediated expression of multiple resistance genes and the production of the penicillinase plasmid TEM-1 [beta]-lactamase are 2 independent mechanisms involved in a susceptible-to-resistant strain switch.
The peptide deformylase inhibitors have shown in vitro activity against Chiamydia species,
gonococci, spirochetes, and Haemophilus ducreyi.
The appropriateness of these recommendations will be reassessed based on surveillance of the prevalence of fluoroquinolone-resistant
gonococci.