The group of antibiotics called fluoroquinolones were used frequently for gonorrhea until a few years ago but are no longer recommended because
gonococcus strains resistant to these drugs have spread worldwide and now are common in the United States.
However, until now there have been no reports on the potential effects of
gonococcus on macrophages.
Biological risk for HIV infection among 253 women attending an anonymous test center for AIDS Total biological risk 200 (n) 79.1 (%) Abnormal vaginal microflora 109 43.1 (bacterial vaginosis) Cervicitis (Chlamydia and
gonococcus) 43 17.0 Vulvovaginitis (candidisis) 43 17.0 HPV infection 22 8.7 Vaginal ulcers 21 8.3 Asymptomatic 151 59.3 Table 3.
It is clear that a new class of therapeutic agent active against the
gonococcus is urgently needed but there are no obvious candidates at present.
(*) BD indicates Becton Dickinson BDProbTec ET; Roche, Roche Amplicor polymerase chain reaction; and GC,
gonococcus.
Culture from the endocervical canal for
gonococcus was negative in all the study subjects.
Gonorrhea is caused by Neisseria gonorrhoeae, also called the
gonococcus. Untreated gonorrhea can cause infertility, especially in women.
Cases were defined as men having urethral discharge on examination and urethral inflammation documented by the presence of >5 polymorphonuclear cells/high power field with absence of any
gonococcus on smear examination after Gram staining and absence of any growth of
gonococcus on culture.
"It's not critical if you see the kid swallow the pill or if you're highly confident of her adherence in taking a prescribed medication." A test of cure may be considered if adherence is questionable, but it's important to wait until at least 3 weeks after treatment if you use a nucleic acid amplification technique to determine the presence of the
gonococcus. "These tests are so sensitive that they can pick up the slightest level of bacteria."
It is generally accepted that conjunctivitis caused by
gonococcus or chlamydia should be suspected in all newborns and in severe cases in sexually active young adults.
But for female patients, a Gram-stained specimen smear is not a reliable means of detecting
gonococcus because other normal vaginal or cervical bacteria can resemble Neisseria.