methylene blue

[′meth·ə‚lēn ′blü]

(organic chemistry)

Dark green crystals or powder; soluble in water (deep blue solution), alcohol, and chloroform; C₁₆H₁₈N₃SCl·3H₂ O used in medicine; (C₁₆H₁₈N₃SCl)₂·ZnCl₂·H₂ O used as a textile dye, biological stain, and indicator. Also known as methylthionine chloride.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Methylene Blue

an organic dye of the thiazine group, used in medicine as an antiseptic and as an antidote for certain types of poisoning.

Methylene blue is applied externally for irrigation and as an ointment for purulent skin conditions; it is taken internally to treat inflammations of the urinary bladder. In addition, it is administered intravenously in glucose solution for cases of hydrocyanic acid, carbon monoxide, and hydrogen sulfide poisoning. Industrially, methylene blue is used in coloring paper, as well as in pencils and printer’s ink.

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References in periodicals archive

Punjabi, Silver(I) Catalyzed photochemical oxidation of methylene blue and safranine-O by peroxydisulphate: A green chemical approach, Int.

Photometric Study of Oxidation of Ascorbic Acid by Methylene Green in Aqueous Alcoholic System

The mechanism of action of methylene blue in the treatment of methemoglobinemia is through the NADPH-MetHb reductase system.

The Incidence of Methemoglobinemia Due to Prilocaine Use in Circumcision/Prilokain ile Yapilan Sunnetlerde Methemoglobinemi Insidansi

Patient was given methylene blue infusion of 1 mg/kg body weight over 20 mins, SP[O.sub.2] improved to 99% at room air.

RARE CASE OF PERSISTENT HYPOXEMIA

The parabasal cells were small round cells with a high nuclear to cytoplasmic ratio and can be seen clearly in clusters when stained with methylene blue. The intermediate cells varied in size and shape as some can be oval with prominent nucleus and others polygonal with lesser nucleus to cytoplasmic ratio .These cells were clearly shown with the Papanicolaou stain than other stains.

Estudio Comparativo de los Metodos de Tincion Metacromatica en la Evaluacion de los Tipos de Celulas Exfoliativas Durante el Ciclo Estral en Ratas Sprague-Dawley de Laboratorio

Methylene blue is used for sentinel node biopsies as it carries a lower risk of allergic reaction than the alternative blue dyes (1,2).

Methylene blue stained reticulocytes in a Giemsa film--a case study

Calibration curve were made with methylene blue solutions at 25, 50, 100, 250, 500 and 1000 mg.[L.sup.-1] concentrations.

ACTIVATED CARBON FROM BAMBOO (Bambusa vulgaris) FOR METHYLENE BLUE REMOVAL: PREDICTION TO THE ENVIRONMENT APPLICATIONS/CARVAO ATIVADO A PARTIR DE BAMBU (Bambusa vulgaris) PARA REMOCAO DE AZUL DE METILENO: PREDICOES PARA APLICACOES AMBIENTAIS

Patients were randomly assigned to receive a full dose of the methylene blue dye, a half dose, or placebo.

A methylene blue dye pill illuminates hard-to-see polyps

For each approach, 1mL plastic syringes filled with 0.2mL of 1% methylene blue dye were used.

Subzygomatic and infraorbital approaches for maxillary nerve blockade in cats' cadaver/Abordagens subzigomatica e infraorbitaria para o bloqueio do nervo maxilar em cadaver de gatos

The methylene blue has a large polar organic molecule [C.sub.16][H.sub.18][N.sub.3][S.sup.+] that can be adsorbed onto the negatively charged surfaces of clay minerals.

Estimation of Soil-Water Characteristic Curve for Cohesive Soils with Methylene Blue Value

The responses analyzed were the yield and adsorption of methylene blue. They were related to calcination temperature and time by a second-order polynomial model given in the following equation:

Optimization of Preparation Conditions of Novel Adsorbent from Sugar Scum Using Response Surface Methodology for Removal of Methylene Blue