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Analysis of the sphingomyelin phosphodiesterase 1 gene (SMPD1) in Turkish Niemann-Pick disease patients: mutation profile and description of a novel mutation.

Initial and Final Status of the Patients with Niemann Pick A and B: Ege University Experience

Carey, "Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers," Gastroenterology, vol.

The Impact of Egg Nutrient Composition and Its Consumption on Cholesterol Homeostasis

There are several ways to generate ceramide in mammalian cells (Figure 1): hydrolysis of sphingomyelin, de novo synthesis from palmitoyl-CoA and serine, catabolism of glucosylceramide and galactosylceramide, synthesis from sphingosine and fatty acid, and dephosphorylation of ceramide-1-phosphate.

Ceramide and Ischemia/Reperfusion Injury

FSGS: Focal segmental glomerulosclerosis GalT-KO: Alpha-1,3-galactosyltransferase knockout HAR: Hyperacute rejection h: Human hDAF: Human decay-accelerating factor MCD: Minimal change disease MHC: Major histocompatibility complex NHP: Nonhuman primates PBL: Peripheral blood lymphocytes POD: Postoperative day SMPDL-3b: Sphingomyelin phosphodiesterase acid-like 3b Tg: Transgenic VTL: Vascularized thymic lobe XKTx: Xenogeneic kidney transplantation.

Remaining Physiological Barriers in Porcine Kidney Xenotransplantation: Potential Pathways behind Proteinuria as well as Factors Related to Growth Discrepancies following Pig-to-Kidney Xenotransplantation

Traditional biomarkers CA 19-9, CEA Proteomics CEMIP, C4BPA, IGFBP2, IGFBP3 Metabolites M2-pyruvate kinase (M2-PK), palmitic acid, glucitol, xylitol, inositol, histidine, proline, sphingomyelin, phosphatidylcholine, isocitrate, ceramide Antibodies immunoglobulin G4 (IgG4) Cytokines interleukin-1[beta], interleukin-6, interleukin-8, interleukin-10, vascular endothelial growth factor and transforming growth factor (macrophage inhibitory cytokine-1 [MIC-1]) Noncoding RNAs (ncRNAs) microRNAs (miRNAs), small ncRNAs (sncRNAs), long ncRNAs (lncRNAs) Liquid biopsy circulating tumor cells (CTCs), circulation tumor DNA (ctDNA) and exosomes Body fluids detecting biomarkers from saliva, urine, stool or pancreatic juice

The Use of Biomarkers in Early Diagnostics of Pancreatic Cancer

Castano, "Sphingomyelin of erythrocytes membranes is related to total cholesterol and LDL-cholesterol in patients with significant coronary arterial disease," The Open Clinical Chemistry Journal, vol.

Study of Erythrocyte Indices, Erythrocyte Morphometric Indicators, and Oxygen-Binding Properties of Hemoglobin Hematoporphyrin Patients with Cardiovascular Diseases

Pearson et al., "Plasma sphingomyelin level as a risk factor for coronary artery disease," Arteriosclerosis Thrombosis and Vascular Biology, vol.

Metabolomic Signature of Coronary Artery Disease in Type 2 Diabetes Mellitus

Atshaves, "Intracellular lipid droplets contain dynamic pools of sphingomyelin: ADRP binds phospholipids with high affinity," Lipids, vol.

Nile Red and 2-NBDG Are Incompatible for the Simultaneous Detection of Lipid and Glucose Accumulation