hyperplasia

[‚hī·pər′plā·zhə]

(medicine)

Increase in cell number causing an increase in the size of a tissue or organ.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Hyperplasia

an increase in the number of structural elements of tissues or organs. In man and animals, hyperplasia is based on the intensified reproduction of cells and the formation of new structures. Hyperplasia is observed in various types of pathological growth of tissues (chronic productive inflammation and tumor), in regeneration, and in hypertrophy. Hyperplasia often carries with it compensating characters. In plants, it may be a local growth of tissues resulting from mitotic or amitotic cell division. It occurs with infection by destructive or pathogenic organisms, during trauma, and under the influence of growth stimulants, pesticides, and other preparations. The result of hyperplasia is the formation of galls, calluses, and warts.

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References in periodicals archive

Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium.

Focal nodular hyperplasia: a weight-based, intraindividual comparison of gadobenate dimeglumine and gadoxetate disodium-enhanced MRI

Takano, "Focal nodular hyperplasia of the liver: Direct evidence of circulatory disturbances," Journal of Gastroenterology and Hepatology, vol.

Development of Focal Nodular Hyperplasia after Cyclophosphamide-Based Chemotherapy in a Patient with Breast Cancer

Oral contraceptive use and focal nodular hyperplasia of the liver.

The Impact of New Technologic and Molecular Advances in the Daily Practice of Gastrointestinal and Hepatobiliary Pathology

This article demonstrates the full spectrum of findings and features of focal nodular hyperplasia in different diagnostic imaging modalities.

Imaging focal nodular hyperplasia

Focal nodular hyperplasia of the liver: MR imaging and pathologic correlation in 37 patients.

Imagenes de resonancia magnetica en el diagnostico diferencial de las lesiones hepaticas mas frecuentes

Focal nodular hyperplasia is the second most common benign tumor of liver after hemangiomas and constitutes 4% of all primary hepatic tumors in pediatric population (2).

Natural course of hepatic focal nodular hyperplasia from childhood to adulthood and review of the literature

Focal nodular hyperplasia is considered a benign lesion that may be a regenerative phenomenon in response to local abnormal blood flow within the liver.

A Triple Stain of Reticulin, Glypican-3, and Glutamine Synthetase: A Useful Aid in the Diagnosis of Liver Lesions

Hepatic adenoma and focal nodular hyperplasia: Differential diagnosis and treatment.

MRI evaluation of masses in the noncirrhotic liver

Historically, the HA-I subtype was referred to as telangiectatic focal nodular hyperplasia and was thought to belong to the FNH family.

Update on the New Classification of Hepatic Adenomas: Clinical, Molecular, and Pathologic Characteristics

Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study.

Confidently characterizing benign liver tumors

Benign lesions include cysts, hemangiomas, focal nodular hyperplasia (FNH), and adenoma, while common malignant lesions include hepatocellular carcinoma (HCC), as well as hyper- and hypovascular metastases.

MR contrast agents: applications in hepatobiliary imaging

Telangiectatic hepatocellular adenomas, formerly termed telangiectatic focal nodular hyperplasia, are uncommon benign liver tumors that constitute 15.4% of lesions diagnosed as focal nodular hyperplasia and demonstrate a mean age at presentation of 38 years and a sex predilection with an 8:1 female to male ratio.

Recent developments in liver pathology