the serous membrane covering the lungs and the walls of the thoracic cavity in higher vertebrates, including man.
Mammals have a pulmonary pleura enveloping the lung, and a parietal pleura lining the inner surface of the thoracic cavity. Within the parietal pleura are the costal, diaphragmatic, and mediastinal pleurae. Between the pulmonary and parietal pleurae is a fissure, the pleural cavity, filled with a fluid that is continually renewed. This fluid is produced mainly by the pulmonary pleura and is absorbed chiefly by the costal part of the parietal pleura. The volume of fluid passing through the pleural cavity in 24 hours is approximately 27 percent of the volume of the blood plasma. The pleural fluid decreases friction between the pleurae during respiration. The sinuses—storage spaces that on inhalation partially fill like lungs and increase in volume—are located between the pleurae, in the inferior part of the pleural cavity. The pleura is supplied with blood from the intercostal, internal thoracic, and diaphragmatic arteries. It is innervated by the vagus, intercostal, and diaphragmatic nerves. Pain receptors are concentrated in the parietal pleura.