Hua et al., "The natriuretic peptides BNP and CNP increase heart rate and electrical conduction by stimulating ionic currents in the
sinoatrial node and atrial myocardium following activation of guanylyl cyclase-linked natriuretic peptide receptors," Journal of Molecular and Cellular Cardiology, vol.
Objective:
Sinoatrial node (SAN) artery originates from proximal segment of right coronary artery (RCA) or from left circumflex artery.
The co-ordinated rhythmic contraction of the heart begins with spontaneous depolarisation of cells in the
sinoatrial node due to diastolic depolarisation and calcium cycling(7,8).
Phase dependency of electrotonic spread of hyperpolarizing current pulses in the rabbit
sinoatrial node // J.
In AF, the atria of the heart are stimulated by abnormal electrical impulses from the
sinoatrial node and malfunctioning atrial tissue, resulting in an irregular and disorganized heart beat.
Origin of the
sinoatrial node and atrioventricular node arteries in right, mixed, and left inferior emphasis systems.
What in the human heart is the purpose of the
sinoatrial node?
This cardiac cycle is regulated by nerve impulses, generated by the heart's internal pacemaker called the
sinoatrial node (SA node), a small bundle of specialized cells located in the right atrium.
In a normally working heart this impulse is generated by the
sinoatrial node (SA node) which is located in the right atrium.