(1969) showed that many genera of microorganisms, including Arthrobacter, Nocardia, Protaminobacter, Serratia, Streptomyces, Mycobacterium, and Microbacterium, contain the enzymes necessary to convert cholesterol and other C-17 sterols to AED and
ADD. Other investigators have shown that microbial degradation of plant sterols and cholesterol can produce ADD (Marsheck et al.