Other amino-acids containing primary
amino group also react with FAA to form Schiff bases and elute from GC column.
Scaffolds containing chitosan and silk fibroin are partially soluble in water, so a glutaraldehyde cross-linking via binding of aldehyde groups with free
amino groups of chitosan and amino acids silk fibroin was performed.
First, it attracted the nucleophilic attack of substrate
amino group on the Schiff-base linkage of PLP.
Although conjugation of organic (drug) molecules to peptides is ideally done while the peptide is bound to the solid support [17], the manyhydroxyl and
amino groups of aminoglycosides render them poorly soluble in the organic solvents where solid phase reactions are best run.
In conclusion, a series of jatrorrhizine derivatives with substituted
amino groups linked at the 3-position were designed, synthesized, and biologically evaluated as inhibitors of acetylcholinesterase.
In IR spectrums of complex tetrafluoroborates the greatest changes are fixed in the field of valent fluctuations of organic ligands
amino groups. Shift values to the low-frequency area of valent asymmetric fluctuations bands of [v.sub.as](N[H.sub.2]) ([DELTA] 180 [cm.sup.-1]) and valent symmetric fluctuations of [v.sub.s](N[H.sub.2]) ([DELTA] 150 [cm.sup.-1]) along with noticeable low-frequency shift in the range of 1590.1610 [cm.sup.-1] allow to speak about bidentate character of OPD in complex of [Cd[(OPD).sub.2]][(B[F.sub.4]).sub.2].
For this step the compound FmocNHNH[(C[H.sub.2]).sub.3]NHBoc (5) was reacted with TFA in DCM to remove the Boc protecting group, and the side-chain
amino group was then converted to [N.sup.[omega]],[N.sup.[omega]]-di-Boc-guanidyl group using N,N'-di-Boc-N"-Tf-guanidine as guanylating reagent in the presence of triethyl amine [20] (Scheme 3).
where N(Lys.) is the lysine unit content in polypeptide or protein, mmol/g; N(N[H.sub.2]) is the free primary
amino group content in polypeptide or protein, mmol/g; wt(Lys.) is the mass fraction of lysine in protein, %; [m.sub.w](Lys.) is the molecular weight of lysine, g/mol; m(protein) is the mass of protein in each recipe, g; m(AAEM) is the mass of AAEM in each recipe, g; [M.sub.w](AAEM) is the molecular weight of AAEM, g.
These PTMs are usually take place at
amino group, hydroxyl group, carboxyl group and side chain of the amino acids.